Dental implant with slow-release drug reservoir reduces infection risk!

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In the latest news, scientists have developed a dental implant containing a reservoir for the slow release of drugs. Laboratory tests in which the reservoir slowly released a strong antimicrobial agent showed that the new implant can prevent and eliminate bacterial biofilms – a major cause of infection associated with dental implants.

Lead author Dr. Kaat De Cremer, from the Centre of Microbial and Plant Genetics at KU Leuven, explains that the reservoir in the implant can be filled by removing the cover screw. She adds that:

“The implant is made of a porous composite material, so that the drugs gradually diffuse from the reservoir to the outside of the implant, which is in direct contact with the bone cells. As a result, the bacteria can no longer form a biofilm.”

In general, bacteria have two life-forms. In one, the planktonic state, they exist as single, independent cells, and in the other, they aggregate in a slime-enclosed mass called a biofilm.

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